Iron metabolism-related genes

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August undefined, 2024

WebThere are few studies on the role of iron metabolism genes in predicting the prognosis of lung adenocarcinoma (LUAD). Therefore, our research aims to screen key genes and to establish a prognostic signature that can predict the overall survival rate of lung adenocarcinoma patients. WebOct 10, 2024 · Hepcidin, a major regulator of systemic iron homeostasis, is mainly induced in hepatocytes by activating bone morphogenetic protein 6 (BMP-6) signaling in response to changes in the iron status. Small heterodimer partner-interacting leucine zipper protein (SMILE), a polyphenol-inducible transcriptional co-repressor, regulates hepatic …

Pharmaceuticals Free Full-Text Modulation of Iron Metabolism …

WebSep 2, 2024 · The iron regulatory proteins (IRP1 and IRP2) are two cytoplasmic RNA-binding proteins involved in the mechanisms that control iron metabolism in mammalian cells. … high long term debt to equity ratio

An overview of molecular basis of iron metabolism regulation and …

WebNational Center for Biotechnology Information WebMay 24, 2024 · Iron supplementation reduced morphological abnormalities of the mitochondria in skeletal muscle and increased the expression of genes related to mitochondrial ETC and energy metabolism in skeletal ... WebOct 1, 2024 · Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies ... Our results support that genetic susceptibility related to the hepcidin-regulating gene pathway is associated with PDAC risk and suggest a potential role of iron metabolism in pancreatic … high look camera

Identification of Iron Metabolism-Related Genes as …

Iron Metabolism and Idiopathic Pulmonary Arterial ... - Hindawi

WebJul 7, 2024 · Fourteen iron metabolism-related gene sets were downloaded from the MSigDB database, yielding 520 iron metabolism-related genes. The final nine hub genes associated with iron metabolism and AD were obtained by differential analysis and WGCNA in brain tissue samples from GSE132903. WebAug 8, 2024 · Iron metabolism is crucial to hepatocellular carcinoma progression and is a key determinant of prognosis. Protein-protein interactions within the iron metabolism … high long window curtain ideaWebOct 22, 2024 · The molecular function of iron metabolism-related genes (IMRGs) is mainly enriched in active transmembrane transporter activity, and they mainly affect the biological process of response to oxidative stress. Ferroptosis and fluid shear stress and atherosclerosis pathways may be the critical pathways regulating iron metabolism in IPAH. high lookee assisted living

"Webwe assessed their expression to reflect iron metabolism by integrating different omics data sources. The data expression profiles of asthma were searched in the Gene Expression Omnibus (GEO) database, and ... Differential expression analysis of iron transport-related genes in discovery and validation datasets (GSE67472 and GSE43696). b) The ... " - Iron metabolism-related genes

Iron metabolism-related genes

Iron Metabolism - an overview ScienceDirect Topics

WebOct 6, 2024 · In this study, we identified candidate genes related to iron (Fe) and zinc (Zn) metabolism through gene expression analysis and correlated it with known QTL regions for GFeC/GZnC. WebMay 28, 2024 · These iron-related COGs include ABC-type cobalamin/Fe 3+ -siderophore transport systems (Mann−Whitney Test, p- value = 0.011), NADPH-dependent ferric siderophore reductases (Mann−Whitney Test,...

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WebIron is an essential nutrient, yet excess iron can be toxic to cells. The uptake of iron by mammalian cells is post-transcriptionally regulated by the interaction of iron-response … WebIron metabolism disorders may involve a number of genes including HFE and TFR2. [1] Hepcidin is the master regulator of iron metabolism and, therefore, most genetic forms of …

WebJul 7, 2024 · In this study, nine genes linking AD and iron metabolism were screened. GO analysis showed that they were involved in autophagy-related and iron metabolism … WebMay 3, 2024 · Iron-related genes were further examined by FeGenie , and Fe-containing domains were characterized using Superfamily (v1.75) . Metagenome taxonomic profiling

WebXVII Summary and Conclusions. Iron metabolism is regulated in cells to ensure that iron supplies are adequate and nontoxic. The expression of iron metabolism is regulated … WebSep 13, 2024 · IRPs regulate the expression of genes involved in iron metabolism by binding to IREs. When cellular iron concentrations are low, the IRPs bind to the IREs, resulting in …

WebFeb 2, 2024 · Hierarchical clustering of the aCGH results on iron metabolism‐related genes recognized differences between Brca1 Mut and the wild‐type in general (Figure S4A). Particularly marked were the changes in Tfr2 , which exhibited more amplification in chrysotile‐induced Brca1 Mut MMs (3/6) than that of the wild‐type (1/6) (Figures 1G and …

WebIn this study, we propose to operate Fe 0-catalyzed microalgae-based MFCs in continuous flow operation mode to explore their antibiotic removal and related biological mechanisms in response to the problems of anode acidification, secondary contamination of cathode electrolyte, and accumulation of antibiotic resistance genes (ARGs) and low efficiency of … high longlandsWebMay 22, 2024 · Sixteen iron metabolism-related gene sets (GO_IRON_ION_BINDING, GO_IRON_ION_IMPORT, GO_IRON_ION_TRANSPORT, GO_RESPONSE_TO_IRON_ION, HEME_BIOSYNTHETIC_PROCESS,HEME_METABOLIC_PROCESS, REACTOME_IRON_UPTAKE_AND_TRANSPORT, … high look cctvWebSep 1, 2024 · Iron is an essential nutrient for almost all living organisms, but is not easily made available. Hosts and pathogens engage in a fight for the metal during an infection, leading to major alterations in the host’s iron metabolism. Important pathological consequences can emerge from the mentioned interaction, including anemia. Several … high lookoutWebMay 3, 2024 · Key metabolic genes were universally present in all samples, including those involved in iron uptake and carbohydrate-active enzymes (CAZymes). We further examined the community-level... high look appWebOct 18, 2024 · Iron metabolism-related genes reveal predictive value of acute coronary syndrome Introduction. Iron deficiency has detrimental effects in patients with acute … high loop dishwasher drain lineWebSep 9, 2024 · Iron metabolism is considered central for glioma tumorigenesis, tumor progression and tumor microenvironment, although key iron metabolism-related genes are unclear. Here we developed and validated an iron metabolism-related gene signature LGG … Loop is the open research network that increases the discoverability and impact … BibTex - Frontiers Identification of Iron Metabolism-Related Genes as ... Reference Manager - Frontiers Identification of Iron Metabolism-Related … Simple Text File - Frontiers Identification of Iron Metabolism-Related Genes as ... work on prostate cancer, Castration resistant prostate cancer and … high loop dishwasher diagramWebJul 1, 2015 · Besides the systemic regulation of iron metabolism mediated by hepcidin, cellular regulatory processes also occur. Cells are able to regulate themselves the expression of the iron metabolism-related genes through different post-transcriptional mechanisms, such as the alternative splicing, microRNAs, the IRP/IRE system and the … high lookout points near me