Grapefruit interaction with statins
WebJun 11, 2024 · Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clin Pharmacol Ther 1998;64:477-83. View abstract. Lilja JJ, Raaska K, Neuvonen PJ. Effects of grapefruit juice on the pharmacokinetics of acebutolol. Br J Clin Pharmacol 2005;60:659-63. WebJan 13, 2016 · A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about 260% if taken at the same time (about 90% if taken 12 hours apart), and atorvastatin by about 80% (whenever …
Grapefruit interaction with statins
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WebHere are examples of some types of drugs that grapefruit juice can cause problems (interact) with: ... For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver and muscle damage that can lead to kidney failure. ... WebNov 18, 2024 · The statins most affected by grapefruit are atorvastatin (Lipitor), lovastatin, and simvastatin (Zocor). Statins that aren’t known to interact with grapefruit include …
WebNov 14, 2024 · Drinking grapefruit juice and taking red yeast rice might increase the risk of the supplement's harmful side effects. Gemfibrozil (Lopid). Taking this cholesterol drug with red yeast rice might increase the risk of myopathy. Hepatotoxic drugs, herbs and supplements. Red yeast rice might contain monacolin K, which can cause liver damage … WebFeb 22, 2024 · Answer From Katherine Zeratsky, R.D., L.D. Yes. Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription …
WebMay 8, 2024 · Grapefruit can increase the side effects of some statin cholesterol medications, causing muscle damage. 4–7: Certain blood pressure medications Most types of blood pressure medicines are not ... WebJan 8, 2015 · MYTH 4 You can't eat grapefruit if you take a statin. Grapefruit does contain compounds that alter how your body processes statins. The compounds, called furanocoumarins, block an enzyme in the intestine that normally breaks down statins (and many other drugs). As a result, more statin gets into the bloodstream, making it more …
WebJan 17, 2024 · But grapefruit's reputation for interfering with some medications is well-deserved. It particularly affects certain anti-cholesterol statin drugs, as well as some …
WebApr 2, 2015 · A: Certain classes of drugs — most notably statins — are metabolized (broken down) in your intestines by an enzyme called … hide my shameWebAug 25, 2024 · Side effects of mixing grapefruit and statins Muscle pain. Also called myalgia, this is the most common statin side effect. Let your healthcare provider know if you... Rhabdomyolysis. This is one of the … hide my shirtWebApplies to: simvastatin. Grapefruit juice can significantly increase the blood levels of simvastatin. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. hide my snap scoreWebConclusion: Grapefruit juice greatly increased serum concentrations of simvastatin and simvastatin acid and, to a lesser extent, those of active and total HMG-CoA reductase … hide my ssidWebHealthier cholesterol levels: Eating plenty of fiber can help keep low-density lipoprotein (LDL) cholesterol in check. ... Grapefruit Side Effects: Who Should Avoid Grapefruit? … hide my taskbar windows 10WebHere are examples of some types of drugs that grapefruit juice can cause problems (interact) with: Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). Some drugs that treat high … hide my subscribers youtubeWebDec 11, 2024 · Out of all the statins, atorvastatin (Lipitor), simvastatin (Zocor), and lovastatin (Altoprev) have the strongest interaction with grapefruit, and this is likely to be true for other citrus. Grapefruit juice and any grapefruit products should be avoided, as should large quantities of limes or lime peel, although small amounts (such as a twist ... hide my text