WebPUB12 and PUB13 are recruited to the FLS2 complex in response to flg22 (Lu et al., 2011). BAK1 phosphorylation of PUB12/PUB13 leads to FLS2 ubiquitination by the E3 ligases for receptor degradation. Consistent with this, FLS2 signaling outputs and bacterial resistance are enhanced in pub12 pub13 plants. Following ligand-induced association WebThe FL2 file extension indicates to your device which app can open the file. However, different programs may use the FL2 file type for different types of data. While we do not …
Current Biology 研究揭示植物受体激酶的免疫信号传导机制 !
WebBAK1 phosphorylates PUB12 and PUB13 and is required for FLS2-PUB12/13 association. PUB12 and PUB13 polyubiquitinate FLS2 and promote flagellin-induced FLS2 degradation, and the pub12 and pub13 mutants displayed elevated immune responses to … WebPUB12 and PUB13 polyubiquitinate FLS2 and promote flagellin-induced FLS2 degradation, and the pub12 and pub13 mutants displayed elevated immune responses to flagellin treatment. Our study has revealed a unique regulatory circuit of direct ubiquitination and turnover of FLS2 by BAK1-mediated phosphorylation and recruitment of specific E3 … dickinson girls softball
Direct ubiquitination of pattern recognition receptor FLS2 …
WebThe Arabidopsis pattern-recognition receptor Flagellin Sensing 2 (FLS2) recognizes bacterial flagellin and initiates immune signaling through association with BAK1. ... et al. Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. USA 2024 ... WebMay 8, 2024 · The Arabidopsis PUB13 has been shown to attenuate the pattern recognition receptor FLS2-mediated immune signaling by ubiquitinating FLS2 and consequently promoting its degradation by the 26S proteasome. Nevertheless, the cognate ubiquitin-conjugating enzymes (E2) with which PUB13 acts to modulate FLS2-mediated PTI are … WebRemarkably, Lu et al. (2011) recently reported that the PRR FLAGELLIN-SENSING2 (FLS2), a LRR receptor-like kinase , is a target of the E3 ligases PUB12 and PUB13 via the UPS. When induced by the bacterial PAMP elicitor flagellin, FLS2 is polyubiquitinated and degraded by PUB12/13. citrine\\u0027s last wish warframe