WebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its … WebFeb 8, 2024 · Introduction. The collagen triple helix repeat containing 1 (Cthrc1) gene was first reported by the Lindner laboratory in a screen for genes differentially expressed upon major damage to arteries in rats (Pyagay et al. 2005).Cthrc1 was highly induced in injured arteries, with expression subsiding upon healing (Pyagay et al. 2005; LeClair et …
Overexpression of CTHRC1 in Hepatocellular Carcinoma Promotes …
WebOct 8, 2012 · Generation of Cthrc1 null mice. (A) Cthrc1 gene targeting schematic showing replacement of exons 2-4 with a PGK-neo cassette. (B) Embryonic stem cell targeting with Southern blot analysis of ... WebELISA Kits by Target . ELISA (enzyme-linked immunosorbent assay) is a plate-based technique for detection and quantification of antibodies or proteins such as cytokines, chemokines, growth factors, hormones, and intracellular phosphorylated proteins. greenville sc back pain
Cthrc1 Is a Novel Inhibitor of Transforming Growth Factor-β …
WebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to ... WebMar 20, 2024 · Correlations between CTHRC1 gene expression and clinicopathological factors were analyzed using gene expression data from UALCAN databases. Then, we searched the GEPIA database to evaluate the association of CTHRC1 gene expression with clinical outcomes. The cBioPortal database was used to analyze CTHRC1 genetic … WebCTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, mutation of the gene has been associated with carcinogenesis in a variety of cell and tissues, most notably esophageal adenocarcinoma and Barrett ... fnf test bonus download apk