Citrate transporter family protein

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August undefined, 2024

WebFeb 11, 2002 · Citrate transport protein (CTP) Mitochondrial citrate carrier 1 publication (CIC 1 publication) Solute carrier family 25 member 1; Tricarboxylate carrier protein; … WebThe citrate carrier (CiC), a nuclear-encoded protein located in the mitochondrial inner membrane, is a member of the mitochondrial carrier family. CiC plays an important role …

Structure and inhibition mechanism of the human citrate …

WebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene . WebJun 14, 2024 · Introduction. L-lactate is an important metabolite in health and disease 1. Its stereoselective transport across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the ... oh holy night by josh groban lyrics

Molecular Mechanism of Citrate Efflux by the …

WebAug 1, 2024 · The recently determined crystal structure of the bacterial Na +-citrate symporter CitS provides unexpected structural and mechanistic insights. The protein has a fold that has not been seen in other proteins, but the oligomeric state, domain organization and proposed transport mechanism strongly resemble those of the sodium … WebSep 29, 2012 · The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family whose members are responsible for the exchange of metabolites, cofactors and nucleotides between the cytoplasm and mitochondrial matrix. Initially, OGC was characterized by determining substrate specificity, kinetic parameters of transport, … WebApr 13, 2024 · The inhibited key enzymes in the citrate cycle highlighted inactive energy ... WU75_10380, WU75_10390, and WU75_10385), encoding a choline ABC transporter ATP-binding protein, a choline ABC transporter substrate-binding protein ... transporter periplasmic adaptor subunit and a multidrug transporter. The RND family efflux pumps ... oh holy night christmas decorations

Structure and elevator mechanism of the Na+-citrate transporter …

The mitochondrial citrate carrier: metabolic role and

WebThe partially compromised nodule functioning induces two striking phenotypes: anthocyanin accumulation already displayed 4 weeks after inoculation and shoot biomass deficiency, which is detected by long-term phenotyping. LjNPF8.6 achieves nitrate uptake in Xenopus laevis oocytes at both 0.5 and 30 mm external concentrations, and a possible role ... WebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity … oh holy night christmas cardWebApr 4, 2024 · The encoded protein may play a role in the formation of kidney stones. [provided by RefSeq, Oct 2016] Other designations. solute carrier family 13 member 2, Na(+)-coupled citrate transporter, Na(+)/dicarboxylate cotransporter 1, renal sodium/dicarboxylate cotransporter, solute carrier family 13 (sodium-dependent … oh holy night christmas carol

"WebSLC25 is the largest solute transporter family in humans. 53 members have been ... (SLC25A1, or citrate transport protein; TC# 2.A.29.7.2) Graves disease carrier protein … " - Citrate transporter family protein

Citrate transporter family protein

SLC13A2 solute carrier family 13 member 2 [ (human)]

WebFeb 23, 2024 · The small molecule citrate is a key molecule that is synthesized de novo and involved in diverse biochemical pathways influencing cell metabolism and function. Citrate is highly abundant in the circulation, and cells take up extracellular citrate via the sodium-dependent plasma membrane transporter NaCT encoded by the SLC13A5 gene. … WebCitrate plays a pivotal role not only in the generation of metabolic energy but also in the synthesis of fatty acids, isoprenoids, and cholesterol in mammalian cells. Plasma levels …

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WebJul 1, 2007 · The cellular transport of long-chain fatty acids (LCFAs) across the plasma membrane has long been thought to occur via passive diffusion. However, in recent years a substantial body of literature has emerged indicating that LCFA uptake into muscle cells occurs via a protein-mediated process (for review see Bonen et al. 2002; Luiken et al. … WebCitrate transporter family protein Imported. Gene names. Ordered locus names. PFL_2499 Imported. Organism names. Organism. Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) Imported. Taxonomic …

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WebMay 14, 2024 · To study the citrate transport mechanism of CT, the citrate transporter gene was expressed in Escherichia coli, and its product was purified. The citrate … WebThis gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate …

WebThis gene encodes a sodium-driven citrate transport protein named NaCT. Disease-causing mutations abolish the uptake of citrate in neurons of the brain. ... (NaDC) from the SLC13 family. A number of mutations have been identified in the NaCT transporter gene (SLC13A5) in patients with epileptic encephalography. The Pajor Lab explores what …

WebApr 7, 2024 · The TaALMT1 gene has been found to belong to a new transporter family and regulates the selective efflux of malate. ... and sorghum [48], and its homologue were then identified as OsFRDL4 (a MATE family citrate transporter) in rice [49 ... (OsSTAR1/2, encodes an ABC transporter protein that forms a complex to regulate the efflux of UDP … oh holy night chords key of gWebJun 1, 2003 · Protein family/group databases. TCDB. 2.A.47.1.9 the divalent anion:na + symporter (dass) family; Names & Taxonomy. Protein names. ... Sodium-coupled citrate transporter 1 publication. Sodium-dependent citrate transporter; Solute carrier family 13 member 5; Gene names. Name. SLC13A5. Synonyms. NACT. Organism names. … my head is burningWebAn insertion in the rice citrate efflux transporter gene OsFRDL4 increased its promoter activity and improved its expression, thereby enhancing Al tolerance ... The PHT family protein PHT5 in the vacuolar membrane regulates cytoplasmic Pi homeostasis to enhance plant growth under Pi deficiency (Lin et al. 2024; ... my head is clear meaningWebOct 29, 2024 · Summary. This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and ... my head is cloggedWebet al., 2004). Functional gene variants of transport proteins are involved in human diseases, and about 10% of established T2D loci are related to membrane transporters. II. Solute Carrier Membrane Transport Proteins Solute carrier (SLC) proteins are a group of trans-membrane transporters that mediate solute influx oh holy night by nat king coleWebWe have characterized a nodule-specific citrate transporter of the multidrug and toxic compound extrusion family, MtMATE67 of Medicago truncatula The MtMATE67 gene was induced early during nodule development and expressed primarily in the invasion zone of mature nodules. The MtMATE67 protein was localized to the plasma membrane of … my head is blown awayWebMar 11, 2016 · Multidrug and toxic compound extrusion (MATE) family is the most recent categorized multidrug efflux transporter family, which is a secondary transporter family that couples the translocation of substrates with an electrochemical gradient of cations (such as H + or Na + ions) across the membrane [1, 2].The X-ray structure of the MATE … oh holy night carol